COVID-19 SARS-CoV-2 Medical Grade Hospital Air Purifier | Aerobiotix

Reducing the Risk of Infection and Contamination in the Operating Room

Medical Grade Hospital Air Purifier

Mitigating SARS-CoV-2 and outbreaks of the future

Our devices have a role in the mitigation of airborne viruses and can be used within CDC guidelines for certain indications.

Using Illuvia® in the operating room
Dr. Rubino, Orthopedic Surgeon

David Kirschman, M.D. Aerobiotix units are wheeled, enclosed hospital-based free-standing air decontamination devices which provide HEPA filtration and ultraviolet germicidal irradiation to the airstream. The devices have undergone independent testing demonstrating 100% inactivation efficiency in viral single-pass testing using the MS2 virus at 450 cubic feet of air per minute. This testing was performed by the Research Triangle Institute and reviewed by the FDA in 2018. Coronavirus is both larger and more radiosensitive than MS2, making it potentially more vulnerable to ultraviolet and mechanical filtration than the MS2 test organism.
Elimination of Aerosolized Virus in Single-Pass Testing In the white paper, researchers from the Research Triangle Institute Center for Microbial Community Systems and Health Research evaluated the viral inactivation performance of an Aerobiotix ultraviolet air handling system. Utilizing the MS2 bacteriophage as a model organism due to its analogous aerosol-related properties to human viruses, the study aimed to measure the efficiency of viral inactivation in a single-pass through the system. The air cleaner was tested under a consistent airflow rate of 450 cubic feet per minute within a test duct setup. The results demonstrated that the device achieved a 100% inactivation rate of the MS2 virus when operated in its full configuration, which includes pre-filtration with a MERV 11 filter, UV-C exposure, and subsequent HEPA filtration. This outcome highlights the potential of the Aerobiotix system for significant viral load reduction in air management applications within healthcare settings.
infection control protocol testimonial

Protecting Patients and Staff Now and in the Future

Illuvia Sense has been substantiated as an effective surgical air decontamination device. This system, which incorporates ultraviolet germicidal irradiation and HEPA filtration, was instrumental during the recent pandemic and continues to protect healthcare settings by maintaining high standards of air purity. Clinical studies have demonstrated the system’s ability to significantly reduce airborne contaminants, including bacteria, viruses, and spores, common in surgical environments.

The Illuvia Sense operates continuously, ensuring that air quality is consistently managed without disrupting medical procedures or staff activities. Its integration into medical facilities is supported by its compliance with existing healthcare protocols, emphasizing its utility, especially in maintaining sterile environments. The device’s impact on reducing surgical site infections highlights its role in enhancing patient safety and reducing transmission risks for healthcare workers worldwide.

Designed For:

Operating Rooms Immunocompromised Care Units Infection Control Facilities High-Activity Surgical Centers Smart Healthcare Facilities Anywhere You Need Air Decontamination


FAST MD Testimonial SARS-CoV-2 Medical Grade Hospital Air Purifier

During the COVID-19 Pandemic, Aerobiotix was pleased to partner with Florida Advanced Spine and Sports Trauma Centers to provide Illuvia ultraclean continuous UV air disinfection systems, creating safe surgical environments for their patients.

“Installing the Illuvia system in our locations has been the best experience. All of the staff at Aerobiotix are responsive and easy to work with. These units are a cost-effective, simple, and efficient solution to reducing infection rates and providing peace of mind that our OR air quality is being addressed.”


Lindsey Wisniewski
MHA, Chief Operating Officer/ Security and Compliance Officer of FASTMD

Shortening the Pause: Calculating Aerosol Clearance for the Illuvia System in the Operating Room Environment


During the COVID-19 pandemic, the resumption of elective procedures required increased vigilance in reducing airborne operating room contamination. Studies have shown that aerosol-generating procedures (AGP), such as intubation, can increase the transmission rates of SARS pathogens by a factor of 13.1

A specific concern is OR turnover times and aerosol clearance between procedures. The use of Aerobiotix HEPA/UV-C Air Recirculation Systems (Illuvia) can have a direct effect on room clearance times, compared to rooms without this technology. Illuvia systems have been independently tested to achieve 100% single-pass virus elimination.2

These systems work in three ways to reduce clearance times:

  • Increasing air exchange rates by 25% compared to baseline airflow.
  • Reducing baseline contamination levels through continuous OR use by 70%.
  • Allowing for relocation in close proximity to aerosol-generating procedures (AGPs).

Determining Baseline Clearance Rate

Air clearance rates are determined by the formula:

T = [ln (C2 / C1) / (Q / V)] X 60

Where T = time in minutes, C1 = initial concentration of contaminant, C2 = final concentration of contaminant, Q = air flow rate in cubic feet/hour, V = room volume in cubic feet.

At baseline, a typical OR, with a flow rate of 100,000 cubic feet/hour, 4750 cubic feet volume, an initial viral concentration of 1000/cubic feet, and a final concentration of 1, will have a clearance rate of 19.7 minutes.

Illuvia: Reduction in initial concentration and increase in flow rate

Published studies3 have found the Illuvia system reduced airborne contamination levels, defined as aerosol particulates between 0.5 to 10 microns. This particulate size range has been identified as a size range for COVID-19 bioaerosols.4

With continuous use in the operative setting, particle contamination was reduced by 70%. Results were achieved with the unit placed 4m from the surgical table, adding an additional 27,000 cubic feet/hour of exchange capacity.

Referring to the clearance formula, the addition of the Illuvia system in the same OR increases the flow rate to 127,000 cubic feet/hour and reduces the initial concentration to 300, resulting in a clearance rate of 12.8 minutes.


Moving Illuvia closer to the contamination source will increase performance

A recent technical report5 from the European Centre for Disease Prevention and Control indicates that in rooms where aerosol-generating procedures have been performed (including intubation and bag-valve ventilation) the use of a portable HEPA air filtration system placed in close proximity to where the patient was located is advised.

Clearance time using the Illuvia can be further reduced by placing the unit near the area where AGPs have been performed. Aerosol concentration will be highest in this location and decrease as an inverse square of the distance from the source:

Placing the unit 1m from the AGP contamination source will capture a much higher proportion of the contamination than at 4m. Temporarily moving the unit from 4m to 1m during intubation and extubation may result in an additional 9x reduction in local aerosol concentration after an AGP is performed. Filtration systems work more efficiently at levels of higher contamination, where a single pass through the system removes relatively more particulates in the same time period.

Referring again to the clearance formula, the addition of the Illuvia system at 1m from a known contamination source with a specific contamination event reduces the initial room concentration to 33, resulting in a clearance rate of 7.8 minutes, assuming that is the only source of contamination.


There is significant variability in operating room construction, airflow, workflow and potential sources and concentrations of contamination. No engineering control can provide a guaranteed result with the inherent variability of the system.  

Moving the Illuvia closer to the contamination source will increase performance

The use of the Illuvia unit in a typical operating room environment will result in a potential reduction in clearance time from 19.7 minutes to 7.8-12.8 minutes. Variability is based on room configuration and the source and level of contamination. If the source can be localized, such as with a specific AGP, higher efficiency may be achieved. It must also be noted that any environmental control system does not substitute for appropriate airborne precautions and wearing of PPE.

Illuvia Sense: Factors for Room Clearance

Reduces baseline particle levels

Increases air exchange rate

Can be placed at the source of contamination

References 1. Fowler RA, Guest CB, Lapinsky SE. Transmission of severe acute respiratory syndrome during intubation and mechanical ventilation. Am J Respir Crit Care Med. 2004 Jun 1;169(11):1198-202. 2. Data on file, Aerobiotix, LLC. 3. Curtis GL, Faour M, Jawad M, Klika AK, Barsoum WK, Higuera CA. Reduction of Particles in the Operating Room Using Ultraviolet Air Disinfection and Recirculation Units. J Arthroplasty. 2018 Jul; 33(7S):S196-S200 4. Wang J, Du G. COVID-19 may transmit though aerosol. Ir J Med Sci. 2020: Mar 24 1-2. 5. European Centre for Disease Prevention and Control. Disinfection of environments in healthcare and non-healthcare settings potentially contaminated with SARS-CoV-2. ECDC: Stockholm; 2020.

“O’Neill said they also are using new Aerobiotix machines in the operating room. “It’s a special device that turns the air over even more frequently in the operating room,” O’Neill explained. “It’s actually got ultraviolet light associated with it and so it eliminates any virus that may be in the OR.”

  Dr. Owen O’Neill Orthopedic Surgeon at Twin Cities Orthopedics

Minnesota Orthopedic Center used Illuvia to kill viruses in operating rooms when elective procedures resumed.

  Read Full Article from
PEER REVIEWED PAPER COVID-19 SARS-CoV-2 Medical Grade Hospital Air Purifier

A mobile device to reduce airborne particulate and prevent surgical site infections

Messina G., et al. Presented at EUPHA 2019

We invite your healthcare facility to experience firsthand the significant benefits of Illuvia Sense with a free trial. Our innovative air decontamination system is tailored specifically for high-risk surgical environments. By participating, your team can observe how Illuvia Sense seamlessly integrates into your current setup, improving air quality and reducing the risk of infection without disrupting ongoing operations.

Contact us today to schedule a complimentary Air Quality Assessment and see the difference Illuvia Sense can make in your operating rooms. Improve your staff and patient care with technology proven to safeguard health.

Register for Our In-Person CE Event at Aerobiotix HQ

Please enable JavaScript in your browser to complete this form.

Place an Order 📞 +1-888-978-7087

Fill in your information below, and one of our representatives will be in touch to help you place your order.

Please enable JavaScript in your browser to complete this form.

Download GermZone Pro Specs 📞 +1-888-978-7087

Please enable JavaScript in your browser to complete this form.

Download AeroCure Vac Specs 📞 +1-888-978-7087

Please enable JavaScript in your browser to complete this form.

Download AeroCure 200 Specs 📞 +1-888-978-7087

Please enable JavaScript in your browser to complete this form.

Download AeroCure Vac Specs

Please enable JavaScript in your browser to complete this form.

Download Illuvia®Sense Specs

Please enable JavaScript in your browser to complete this form.

Download AeroCure Vac Specs 📞 +1-888-978-7087

Please enable JavaScript in your browser to complete this form.

Download Illuvia®Sense Specs 📞 +1-888-978-7087

Please enable JavaScript in your browser to complete this form.